Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS05904.1Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: bpm:BURPS1710b_A0944 5.9e-40 short chain dehydrogenase K00079; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score: 9.98. (271 aa)    
Predicted Functional Partners:
EDS05903.1
Hypothetical protein; KEGG: bce:BC1788 7.0e-60 lysophospholipase L2 K01048; COG: COG2267 Lysophospholipase; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.574
PrpC2
KEGG: lla:L67186 6.4e-137 gltA; citrate synthase K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score: 9.98.
     
 0.572
SrfAA
AMP-binding enzyme; KEGG: ava:Ava_1613 5.8e-204 non-ribosomal peptide synthase K00644; COG: COG1020 Non-ribosomal peptide synthetase modules and related proteins; Psort location: Cytoplasmic, score: 9.96; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.560
fabD
[acyl-carrier-protein] S-malonyltransferase; KEGG: cac:CAC3575 2.1e-74 fabD; malonyl CoA-acyl carrier protein transacylase K00645; COG: COG0331 (acyl-carrier-protein) S-malonyltransferase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.497
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
   
 
 0.487
fabF
Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.455
EDS05900.1
Hypothetical protein.
       0.450
ycfH
Hydrolase, TatD family; KEGG: bli:BL00532 1.1e-63 yabD; TatD-related deoxyribonuclease K03424; COG: COG0084 Mg-dependent DNase; Psort location: Cytoplasmic, score: 8.87.
       0.425
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
  
 0.406
PpiB
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 
 0.405
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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