Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDS05692.1Metallo-beta-lactamase family protein; KEGG: hch:HCH_02525 0.00021 Zn-dependent hydrolase, including glyoxylases K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases. (117 aa)    
Predicted Functional Partners:
EDS05691.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.773
icaR
Transcriptional regulator, TetR family; COG: NOG38831 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.636
EDS05694.1
COG: COG4905 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.548
noxE
NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98.
   
 0.542
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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