Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fldC_22-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 3.4e-60 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. (425 aa)    
Predicted Functional Partners:
hgdC
Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 2.1e-42 yjiL; hypothetical protein YjiL K04111; COG: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); Psort location: Cytoplasmic, score: 8.87.
 
 0.948
EDS05700.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.920
hadI
Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 1.6e-18 yjiL; hypothetical protein YjiL K04111; COG: COG3580 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.576
yedF
Selenium metabolism protein YedF; COG: NOG13230 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87; Belongs to the sulfur carrier protein TusA family.
 
    0.565
sufS_2
Cysteine desulfurase family protein; KEGG: tde:TDE2460 1.5e-87 aminotransferase, class V; COG: COG0520 Selenocysteine lyase; Psort location: Cytoplasmic, score: 8.87.
 
     0.554
proX_2
Hypothetical protein; KEGG: pfa:PFL0670c 8.7e-17 Bi-functional aminoacyl-tRNA synthetase, putative K01881:K01885; COG: COG3760 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.501
EDS06627.1
Hypothetical protein; KEGG: lma:LmjF28.1160 0.0014 vacuolar type H+ ATPase subunit, putative K02155; COG: COG2391 Predicted transporter component; Psort location: CytoplasmicMembrane, score: 9.99.
 
    0.403
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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