Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS05723.1HNH endonuclease domain protein; KEGG: eco:b1159 1.2e-18 mcrA, rglA, ponA; e14 prophage; restriction of DNA at 5-methylcytosine residues K07451; COG: COG1403 Restriction endonuclease; Psort location: Cytoplasmic, score: 8.87. (277 aa)    
Predicted Functional Partners:
EDS05722.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.609
EDS05724.1
Hypothetical protein; COG: NOG15747 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.431
mcrB
ATPase family associated with various cellular activities (AAA); KEGG: neu:NE2528 4.8e-77 AAA ATPase superfamily K07452; COG: COG1401 GTPase subunit of restriction endonuclease; Psort location: Cytoplasmic, score: 8.87.
     
 0.408
EDS05721.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.402
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (22%) [HD]