Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS05737.1Response regulator receiver domain protein; KEGG: bur:Bcep18194_C7173 7.9e-17 two component transcriptional regulator, AraC family; COG: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. (507 aa)    
Predicted Functional Partners:
ypdA_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: tte:TTE2344 2.0e-46 lytS2; predicted ATPase K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.976
AraN_1
ABC transporter, solute-binding protein; KEGG: eci:UTI89_C1581 3.0e-07 ycjN; putative ABC transporter periplasmic binding protein YcjN precursor K02027; COG: COG1653 ABC-type sugar transport system, periplasmic component; Psort location: Cytoplasmic, score: 8.87.
 
     0.896
ypdA_4
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bld:BLi01366 5.0e-43 yesM; similar to two-component sensor histidine kinase [YesN]; RBL02409 K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.808
ypdA_3
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: tte:TTE2344 7.8e-45 lytS2; predicted ATPase K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.791
yehU_2
HAMP domain protein; KEGG: bha:BH3447 4.8e-61 two-component sensor histidine kinase K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
 
 
 0.788
ypdA_1
HAMP domain protein; KEGG: bld:BLi01366 3.7e-70 yesM; similar to two-component sensor histidine kinase [YesN]; RBL02409 K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
 
 
 0.760
yehU_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bld:BLi00440 1.4e-40 putative ABC transporter (permease); RBL00398 K07718; COG: COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.748
EDS05736.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.682
cckA
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 
 0.544
zraS_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: eco:b2219 1.7e-25 atoS; sensor protein AtoS for response regulator AtoC K07710; COG: COG2202 FOG: PAS/PAC domain; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
   0.523
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (20%) [HD]