Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cysBKEGG: shn:Shewana3_3435 1.5e-07 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family. (307 aa)    
Predicted Functional Partners:
EDS05784.1
Hypothetical protein.
       0.741
pyk-2
Pyruvate kinase; KEGG: tte:TTE1815 8.7e-133 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
     
 0.495
KtrA_3
TrkA N-terminal domain protein; KEGG: cps:CPS_4387 0.00033 gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase K00057; COG: COG0569 K+ transport systems, NAD-binding component; Psort location: CytoplasmicMembrane, score: 7.80.
       0.458
ktrB_2
KEGG: ama:AM1116 6.5e-08 trkH; potassium uptake protein K03498; COG: COG0168 Trk-type K+ transport systems, membrane components; Psort location: CytoplasmicMembrane, score: 10.00.
       0.450
secF
Export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
       0.450
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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