Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS05792.1Hypothetical protein; COG: NOG21554 non supervised orthologous group. (466 aa)    
Predicted Functional Partners:
Ogt
6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.608
cynR_2
LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 8.0e-14 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family.
  
    0.569
EDS05790.1
Hypothetical protein; KEGG: zmo:ZMO0053 2.3e-15 pcaD; putative beta-ketoadipate enol-lactone hydrolase K01055; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Psort location: Cytoplasmic, score: 8.87.
   
   0.416
AdeQ
Putative permease; KEGG: bcz:BCZK0244 3.5e-65 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; COG: COG2252 Permeases; Psort location: CytoplasmicMembrane, score: 9.99.
       0.404
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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