Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HtrB_1PDZ/DHR/GLGF domain protein; KEGG: chy:CHY_0655 2.3e-29 htrA; serine protease Do; COG: COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (443 aa)    
Predicted Functional Partners:
HtrB_2
PDZ/DHR/GLGF domain protein; KEGG: chy:CHY_0655 1.0e-60 htrA; serine protease Do; COG: COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
  
  
 
0.926
yhaM
HDIG domain protein; COG: COG3481 Predicted HD-superfamily hydrolase; Psort location: Cytoplasmic, score: 8.87.
       0.777
phoR_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00191 1.3e-58 sensory transduction histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.722
rumA-2
23S rRNA (uracil-5-)-methyltransferase RumA; KEGG: bha:BH0687 1.9e-121 RNA methyltransferase K00599; COG: COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
  
    0.686
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.603
EDS04908.1
PspC domain protein; COG: COG1983 Putative stress-responsive transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.602
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
 0.597
glpK_2
Putative glycerol kinase; KEGG: chy:CHY_1839 4.9e-123 glpK; glycerol kinase K00864; COG: COG0554 Glycerol kinase; Psort location: Cytoplasmic, score: 8.87.
   
 0.597
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.593
mutS2_1
MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
       0.589
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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