Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
topB_1DNA topoisomerase; KEGG: efa:EF2312 3.7e-189 topB-2; DNA topoisomerase III K03169; COG: COG0550 Topoisomerase IA; Psort location: Cytoplasmic, score: 8.87. (694 aa)    
Predicted Functional Partners:
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
   0.805
recQ
KEGG: cpf:CPF_0327 4.3e-140 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.87.
 
 0.803
EDS05581.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.552
EDS05575.1
Hypothetical protein; COG: COG3451 Type IV secretory pathway, VirB4 components; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.525
EDS08782.1
Hypothetical protein; COG: COG3451 Type IV secretory pathway, VirB4 components.
 
  
 0.504
EDS05573.1
Hypothetical protein; COG: NOG28113 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.75.
 
     0.477
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.474
EDS08784.1
Hypothetical protein; COG: NOG28113 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.473
EDS05579.1
LPXTG-motif cell wall anchor domain protein; COG: NOG36404 non supervised orthologous group.
 
     0.449
EDS05589.1
Hypothetical protein; COG: COG3843 Type IV secretory pathway, VirD2 components (relaxase); Psort location: Cytoplasmic, score: 8.87.
 
 
   0.447
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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