Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ltrA-2Group II intron-encoded protein LtrA; KEGG: spi:MGAS10750_Spy1709 2.2e-120 reverse transcriptase / RNA maturase / endonuclease K00986; COG: COG3344 Retron-type reverse transcriptase; Psort location: Cytoplasmic, score: 8.87. (600 aa)    
Predicted Functional Partners:
EDS07406.1
Reverse transcriptase (RNA-dependent DNA polymerase); KEGG: rba:RB818 3.1e-10 reverse transcriptase/maturase K00986; COG: COG3344 Retron-type reverse transcriptase; Psort location: Cytoplasmic, score: 8.87.
  
     0.768
EDS06339.1
Hypothetical protein; KEGG: pol:Bpro_5394 1.0e-09 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase.
  
     0.739
EDS05591.1
Hypothetical protein.
       0.671
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
      
 0.618
EDS05589.1
Hypothetical protein; COG: COG3843 Type IV secretory pathway, VirD2 components (relaxase); Psort location: Cytoplasmic, score: 8.87.
  
  
 0.462
EDS05588.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.404
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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