Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDS05611.1Sigma-70, region 4; Psort location: Cytoplasmic, score: 8.87. (170 aa)    
Predicted Functional Partners:
EDS05610.1
RNA polymerase sigma factor, sigma-70 family; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.896
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.867
rsbT
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: mav:MAV_0432 1.2e-11 serine/threonine-protein kinase RsbT K08282; COG: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Psort location: Cytoplasmic, score: 8.87.
  
 
 0.867
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.864
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.862
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.861
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.860
EDS05607.1
Hypothetical protein; COG: NOG19743 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.842
Pre
Plasmid recombination enzyme; COG: NOG17369 non supervised orthologous group.
 
   
 0.790
EDS06228.1
Sigma-70, region 4; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.769
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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