Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hsdSKEGG: dde:Dde_2496 4.1e-48 subunit S of type I restriction-modification system K01154; COG: COG0732 Restriction endonuclease S subunits; Psort location: Cytoplasmic, score: 8.87. (487 aa)    
Predicted Functional Partners:
EDS05635.1
N-6 DNA Methylase; KEGG: dde:Dde_2498 1.6e-94 type I restriction-modification system, M subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.995
EDS05636.1
Hypothetical protein; KEGG: ana:alr3475 6.3e-43 type I restriction modification enzyme M subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit.
 
 
 0.990
radD
KEGG: noc:Noc_3028 1.8e-253 type I restriction enzyme, R subunit K01153; COG: COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.954
hsdM
KEGG: tde:TDE0369 2.0e-245 hsdM-1; type I restriction-modification system, M subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.936
hsdR
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.829
EDS05633.1
Putative toxin-antitoxin system, toxin component; COG: NOG16461 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.794
EDS06198.1
Hypothetical protein; COG: COG4646 DNA methylase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.775
EDS05616.1
N-6 DNA Methylase; KEGG: chu:CHU_1468 6.8e-12 dpn; possible adenine-specific DNA methylase K00599; COG: COG4646 DNA methylase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.775
mcrB
ATPase family associated with various cellular activities (AAA); KEGG: neu:NE2528 4.8e-77 AAA ATPase superfamily K07452; COG: COG1401 GTPase subunit of restriction endonuclease; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.712
EDS05632.1
Hypothetical protein; KEGG: fnu:FN0307 0.0088 fecE; iron(III) dicitrate transport ATP-binding protein fecE K02013; COG: COG4938 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.707
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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