Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pgsA_2CDP-alcohol phosphatidyltransferase; KEGG: pmi:PMT9312_0806 1.5e-11 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995; COG: NOG21728 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (180 aa)    
Predicted Functional Partners:
cinA_2
Competence/damage-inducible domain protein CinA; KEGG: hsa:80308 5.5e-07 FLAD1; FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae) K00953; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
  
  
 0.819
EDS05490.1
KEGG: bca:BCE_3047 1.6e-05 glyoxalase family protein K01759; COG: COG0346 Lactoylglutathione lyase and related lyases.
  
    0.786
EDS05487.1
Hydrolase, carbon-nitrogen family; KEGG: bur:Bcep18194_A4513 0.0037 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K01950; COG: COG0388 Predicted amidohydrolase.
       0.775
EDS05488.1
Hypothetical protein; KEGG: hhe:HH1444 5.8e-19 guaA; guanosine monophosphate synthetase GuaA K01951; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.
       0.775
EDS07617.1
DNA-binding helix-turn-helix protein; COG: COG1396 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
  
    0.662
tag
KEGG: pha:PSHAa0788 4.5e-42 tag; 3-methyl-adenine DNA glycosylase I K01246; COG: COG2818 3-methyladenine DNA glycosylase; Psort location: Cytoplasmic, score: 8.87.
       0.655
folD
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
  
 0.484
nnr
YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
  
  
 0.479
EDS05484.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
 
     0.472
EDS05486.1
Hypothetical protein; COG: COG1961 Site-specific recombinases, DNA invertase Pin homologs; Psort location: Cytoplasmic, score: 8.87.
       0.424
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (28%) [HD]