STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tagKEGG: pha:PSHAa0788 4.5e-42 tag; 3-methyl-adenine DNA glycosylase I K01246; COG: COG2818 3-methyladenine DNA glycosylase; Psort location: Cytoplasmic, score: 8.87. (213 aa)    
Predicted Functional Partners:
Ogt
6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
   
 0.711
EDS05490.1
KEGG: bca:BCE_3047 1.6e-05 glyoxalase family protein K01759; COG: COG0346 Lactoylglutathione lyase and related lyases.
  
    0.667
EDS05488.1
Hypothetical protein; KEGG: hhe:HH1444 5.8e-19 guaA; guanosine monophosphate synthetase GuaA K01951; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.
       0.663
EDS05487.1
Hydrolase, carbon-nitrogen family; KEGG: bur:Bcep18194_A4513 0.0037 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K01950; COG: COG0388 Predicted amidohydrolase.
       0.661
pgsA_2
CDP-alcohol phosphatidyltransferase; KEGG: pmi:PMT9312_0806 1.5e-11 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995; COG: NOG21728 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.655
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.610
EDS05492.1
Fic family protein; COG: COG2184 Protein involved in cell division; Psort location: Cytoplasmic, score: 8.87.
       0.404
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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