STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macB_4KEGG: pen:PSEEN3042 6.1e-05 macB; macrolide ABC efflux protein MacB; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.39. (479 aa)    
Predicted Functional Partners:
yxdL_2
ABC transporter, ATP-binding protein; KEGG: psb:Psyr_0081 4.1e-32 ABC transporter K02045; COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.82.
 
   0.900
EDS05508.1
Efflux ABC transporter, permease protein; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.26.
 
    
0.839
EDS05507.1
Hypothetical protein.
       0.755
EDS05510.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.727
EDS05503.1
GtrA family protein; KEGG: fnu:FN1094 2.8e-24 dolichol-phosphate mannosyltransferase K00721; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: Cytoplasmic, score: 8.87.
 
     0.461
EDS05511.1
Hypothetical protein; Psort location: Extracellular, score: 7.50.
       0.459
norM
MATE efflux family protein; COG: COG0534 Na+-driven multidrug efflux pump; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.414
phoR_5
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2750 8.8e-69 histidine kinase, putative; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
  
    0.402
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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