Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SipW_2Signal peptidase I; KEGG: cpr:CPR_2281 1.3e-21 sipW; signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.75. (162 aa)    
Predicted Functional Partners:
SipW_1
KEGG: cpr:CPR_0480 6.3e-20 peptidase, putative K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.75.
  
  
 
0.917
EDS05523.1
Hypothetical protein.
  
    0.798
EDS05524.1
Hypothetical protein; Psort location: Cellwall, score: 9.98.
       0.789
mscL-2
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.717
EDS05526.1
Hypothetical protein.
       0.685
EDS05521.1
Hypothetical protein.
  
    0.643
EDS05527.1
Hypothetical protein.
       0.603
EDS05528.1
Hypothetical protein; KEGG: cac:CAC3375 7.7e-14 alcohol dehydrogenase K00001:K00121; COG: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; Psort location: Cytoplasmic, score: 8.87.
       0.576
minE
Putative cell division topological specificity factor MinE; Psort location: Cytoplasmic, score: 8.87.
   
    0.550
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.528
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.