STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mscL-2Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (135 aa)    
Predicted Functional Partners:
EDS05526.1
Hypothetical protein.
       0.746
EDS05524.1
Hypothetical protein; Psort location: Cellwall, score: 9.98.
       0.713
SipW_2
Signal peptidase I; KEGG: cpr:CPR_2281 1.3e-21 sipW; signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.75.
       0.709
EDS05523.1
Hypothetical protein.
       0.709
EDS05527.1
Hypothetical protein.
       0.655
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
    0.643
EDS05528.1
Hypothetical protein; KEGG: cac:CAC3375 7.7e-14 alcohol dehydrogenase K00001:K00121; COG: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; Psort location: Cytoplasmic, score: 8.87.
       0.625
EDS05521.1
Hypothetical protein.
       0.544
EDS05529.1
Hypothetical protein.
       0.542
EDS05519.1
Hypothetical protein.
       0.416
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.