STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ThiFThiF family protein; KEGG: eca:ECA0230 1.2e-34 thiF; thiamine biosynthesis adenylyltransferase K03148; COG: COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; Psort location: Cytoplasmic, score: 8.87. (396 aa)    
Predicted Functional Partners:
thiS
COG: COG2104 Sulfur transfer protein involved in thiamine biosynthesis; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.984
EDS05436.1
ThiS family protein; COG: COG1977 Molybdopterin converting factor, small subunit; Psort location: Cytoplasmic, score: 8.87.
  
 0.981
iscS_2
Aminotransferase, class V; KEGG: tte:TTE1663 8.8e-101 nifS; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes K04487; COG: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Psort location: Cytoplasmic, score: 8.87.
   
 0.930
nifS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 0.930
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.880
Mog_1
Molybdenum cofactor synthesis domain protein; KEGG: hpa:HPAG1_0784 4.0e-25 molybdopterin biosynthesis protein; COG: COG0521 Molybdopterin biosynthesis enzymes; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.873
EDS05429.1
Hypothetical protein; COG: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; Psort location: CytoplasmicMembrane, score: 9.87.
  
  
 0.789
malK
ABC transporter, ATP-binding protein; KEGG: pfo:Pfl_4466 6.8e-23 ABC transporter-like K02052; COG: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
  
    0.779
SsuC_2
ABC transporter, permease protein; KEGG: lwe:lwe0999 0.0030 gbuB; glycine betaine/L-proline ABC transporter, permease protein; COG: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
       0.777
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.698
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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