STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpaIIMModification methylase HpaII; KEGG: mpe:MYPE9800 3.9e-75 cytosine-specific DNA methylase K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87. (405 aa)    
Predicted Functional Partners:
dcm-2
KEGG: cac:CAC1222 4.8e-100 DNA-methyltransferase (cytosine-specific) K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.
 
  
 
0.932
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.910
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.901
moeA_2
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
    0.723
tupB
Putative ATP synthase F0, A subunit; KEGG: pac:PPA0505 1.2e-12 ABC transporter, putative molybdenum transport system K02017:K02018; COG: COG4662 ABC-type tungstate transport system, periplasmic component; Psort location: CytoplasmicMembrane, score: 10.00.
       0.707
tupC
KEGG: bbr:BB1043 1.2e-23 ATP-binding component of ABC transporter K02010; COG: COG3839 ABC-type sugar transport systems, ATPase components; Psort location: CytoplasmicMembrane, score: 9.49.
       0.707
moeA_1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
    0.707
vsr
DNA mismatch endonuclease Vsr; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.
 
   
 0.701
tupA
Tungstate ABC transporter, tungstate-binding protein; COG: COG2998 ABC-type tungstate transport system, permease component.
       0.662
EDS05442.1
Hypothetical protein.
       0.484
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.