STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vsrDNA mismatch endonuclease Vsr; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. (157 aa)    
Predicted Functional Partners:
hpaIIM
Modification methylase HpaII; KEGG: mpe:MYPE9800 3.9e-75 cytosine-specific DNA methylase K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.701
dcm-2
KEGG: cac:CAC1222 4.8e-100 DNA-methyltransferase (cytosine-specific) K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.611
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 
 0.599
EDS05451.1
EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
       0.592
dcm
DNA (cytosine-5-)-methyltransferase; KEGG: san:gbs1370 1.3e-37 similar to methyl transferase K00558; COG: COG0270 Site-specific DNA methylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
   
 0.565
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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