Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hsdRType I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1060 aa)    
Predicted Functional Partners:
EDS05383.1
Type I restriction modification DNA specificity domain protein; KEGG: mba:Mbar_A1015 3.5e-42 putative type I restriction enzyme, S subunit K01154; COG: COG0732 Restriction endonuclease S subunits.
 
  
 0.981
hsdM
KEGG: tde:TDE0369 2.0e-245 hsdM-1; type I restriction-modification system, M subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.980
EDS05385.1
Hypothetical protein; KEGG: hpa:HPAG1_1468 2.5e-20 hypothetical protein; COG: COG1451 Predicted metal-dependent hydrolase; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.952
EDS05387.1
Hypothetical protein; COG: NOG18152 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
   0.878
EDS05386.1
Hypothetical protein; COG: COG1479 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
 
   0.842
hsdS
KEGG: dde:Dde_2496 4.1e-48 subunit S of type I restriction-modification system K01154; COG: COG0732 Restriction endonuclease S subunits; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.829
EDS05381.1
DNA binding domain, excisionase family; KEGG: rba:RB5795 0.0022 ptsN; probable PTS system, fructose-specific IIABC component K02806; COG: NOG17802 non supervised orthologous group.
 
     0.827
EDS05845.1
Hypothetical protein; KEGG: bba:Bd3704 2.5e-17 putative zinc metallo protease; COG: COG1451 Predicted metal-dependent hydrolase; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.778
EDS05635.1
N-6 DNA Methylase; KEGG: dde:Dde_2498 1.6e-94 type I restriction-modification system, M subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.758
EDS05636.1
Hypothetical protein; KEGG: ana:alr3475 6.3e-43 type I restriction modification enzyme M subunit K03427; COG: COG0286 Type I restriction-modification system methyltransferase subunit.
  
  
 0.692
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.