| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PurL | guaA | CLOSCI_01211 | CLOSCI_03102 | Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.978 |
| PurL | guaA-2 | CLOSCI_01211 | CLOSCI_03505 | Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87. | GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 2.8e-184 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score: 8.87. | 0.978 |
| PurL | ileS | CLOSCI_01211 | CLOSCI_02632 | Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87. | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.594 |
| PurL | lysS | CLOSCI_01211 | CLOSCI_00952 | Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87. | lysine--tRNA ligase; KEGG: tte:TTE2372 6.7e-158 lysU; lysyl-tRNA synthetase class II K04567; COG: COG1190 Lysyl-tRNA synthetase (class II); Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.693 |
| PurL | pheT | CLOSCI_01211 | CLOSCI_03570 | Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87. | KEGG: cno:NT01CX_1768 1.5e-199 pheT; phenylalanyl-tRNA synthetase, beta subunit K01888; COG: COG0073 EMAP domain; Psort location: Cytoplasmic, score: 9.98. | 0.964 |
| PurL | rpoB | CLOSCI_01211 | CLOSCI_00847 | Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.674 |
| PurL | sun | CLOSCI_01211 | CLOSCI_02807 | Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.644 |
| guaA | PurL | CLOSCI_03102 | CLOSCI_01211 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87. | 0.978 |
| guaA | guaA-2 | CLOSCI_03102 | CLOSCI_03505 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 2.8e-184 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score: 8.87. | 0.935 |
| guaA | ileS | CLOSCI_03102 | CLOSCI_02632 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.692 |
| guaA | leuS | CLOSCI_03102 | CLOSCI_03648 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | leucine--tRNA ligase; KEGG: bsu:BG10676 5.8e-239 leuS; leucyl-tRNA synthetase K01869; COG: COG0495 Leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.503 |
| guaA | lysS | CLOSCI_03102 | CLOSCI_00952 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | lysine--tRNA ligase; KEGG: tte:TTE2372 6.7e-158 lysU; lysyl-tRNA synthetase class II K04567; COG: COG1190 Lysyl-tRNA synthetase (class II); Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.899 |
| guaA | pheS | CLOSCI_03102 | CLOSCI_03569 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | KEGG: cpr:CPR_1852 5.2e-119 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889; COG: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Psort location: Cytoplasmic, score: 10.00. | 0.620 |
| guaA | pheT | CLOSCI_03102 | CLOSCI_03570 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | KEGG: cno:NT01CX_1768 1.5e-199 pheT; phenylalanyl-tRNA synthetase, beta subunit K01888; COG: COG0073 EMAP domain; Psort location: Cytoplasmic, score: 9.98. | 0.879 |
| guaA | rpoB | CLOSCI_03102 | CLOSCI_00847 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.844 |
| guaA | sun | CLOSCI_03102 | CLOSCI_02807 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.514 |
| guaA-2 | PurL | CLOSCI_03505 | CLOSCI_01211 | GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 2.8e-184 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score: 8.87. | Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87. | 0.978 |
| guaA-2 | guaA | CLOSCI_03505 | CLOSCI_03102 | GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 2.8e-184 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score: 8.87. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.935 |
| guaA-2 | ileS | CLOSCI_03505 | CLOSCI_02632 | GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 2.8e-184 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score: 8.87. | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.692 |
| guaA-2 | leuS | CLOSCI_03505 | CLOSCI_03648 | GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 2.8e-184 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score: 8.87. | leucine--tRNA ligase; KEGG: bsu:BG10676 5.8e-239 leuS; leucyl-tRNA synthetase K01869; COG: COG0495 Leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.503 |