Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
regX3_2Response regulator receiver domain protein; KEGG: fal:FRAAL1628 2.2e-26 response regulator in two-component regulatory system; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. (223 aa)    
Predicted Functional Partners:
resE_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC01918 8.0e-36 resE; sensor protein ResE; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
   0.950
baeS
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC01918 1.4e-38 resE; sensor protein ResE; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
   0.756
EDS04965.1
Hypothetical protein.
       0.723
EDS04969.1
Efflux ABC transporter, permease protein; KEGG: cch:Cag_0337 0.00081 ATPase K06020; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.718
MprB
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
   0.677
regX3_3
Transcriptional regulatory protein, C-terminal domain protein; KEGG: fal:FRAAL1628 1.5e-16 response regulator in two-component regulatory system; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
     0.675
cckA
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 0.620
WalK_4
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: btl:BALH_4249 3.7e-47 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 0.590
resE_7
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 6.8e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
   0.581
bceA_1
ABC transporter, ATP-binding protein; KEGG: fal:FRAAL2864 1.6e-46 putative transport protein of outer membrane lipoproteins (ABC superfamily, atp_bind) (partial match); COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
       0.572
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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