Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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Score
cobU_2Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; KEGG: cps:CPS_3657 1.9e-18 cobP; bifunctional cobalamin biosynthesis protein CobP K02231; COG: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 8.87. (179 aa)    
Predicted Functional Partners:
cobS
Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.997
cobU_1
Hypothetical protein; KEGG: eco:b1993 2.6e-14 cobU; bifunctional: cobinamide kinase; cobinamide phosphate guanylyltransferase K02231; COG: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 8.87.
  
  0.996
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 
 0.996
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
  
 0.983
cobB
KEGG: tte:TTE0375 2.4e-75 cobB; Cobyrinic acid a,c-diamide synthase K03401; COG: COG1797 Cobyrinic acid a,c-diamide synthase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.981
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.975
btuR
Putative cob(I)yrinic acid a,c-diamide adenosyltransferase; KEGG: tte:TTE0370 2.2e-26 btuR; ATP:corrinoid adenosyltransferase K00798; COG: COG2109 ATP:corrinoid adenosyltransferase; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.963
cobK
precorrin-6A reductase; KEGG: ctc:CTC00734 5.1e-57 cbiT; precorrin-6B methylase/decarboxylase cbiT/cbiE K03399:K02191; COG: COG2241 Precorrin-6B methylase 1; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.952
cobJ
KEGG: lmo:lmo1199 7.6e-63 cbiH; precorrin-3B C17-methyltransferase K03395; COG: COG1010 Precorrin-3B methylase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.931
pspB
Phosphoglycerate mutase family protein; KEGG: cpe:CPE1038 2.5e-25 cobC; probable alpha-ribazole-5'-phosphate phosphatase K02226; COG: COG0406 Fructose-2,6-bisphosphatase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.929
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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