STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SirCSiroheme synthase domain protein; KEGG: aae:aq_1237 6.8e-23 cysG; precorrin-2 oxidase. (163 aa)    
Predicted Functional Partners:
cbiK
Cobalt chelatase (CbiK); KEGG: lin:lin1165 4.1e-55 cbiK; similar to anaerobic Cobalt Chelatase In Cobalamin Biosynthesis K02190; COG: COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 
 0.999
cobI
KEGG: mst:Msp_0038 1.4e-31 cbiL; CbiL K03394; COG: COG2243 Precorrin-2 methylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the precorrin methyltransferase family.
 
 
 0.995
hemB
Porphobilinogen synthase; KEGG: aae:aq_2109 1.1e-102 hemB; delta-aminolevulinic acid dehydratase K01698; COG: COG0113 Delta-aminolevulinic acid dehydratase; Psort location: Cytoplasmic, score: 8.87; Belongs to the ALAD family.
 
   
 0.970
cobJ
KEGG: lmo:lmo1199 7.6e-63 cbiH; precorrin-3B C17-methyltransferase K03395; COG: COG1010 Precorrin-3B methylase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.946
cbiG
CbiG; KEGG: dde:Dde_3181 1.8e-33 precorrin-3B C17-methyltransferase K02189:K03395:K00594; COG: COG2073 Cobalamin biosynthesis protein CbiG; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.941
cobK
precorrin-6A reductase; KEGG: ctc:CTC00734 5.1e-57 cbiT; precorrin-6B methylase/decarboxylase cbiT/cbiE K03399:K02191; COG: COG2241 Precorrin-6B methylase 1; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.932
cobH
KEGG: gsu:GSU2999 1.1e-45 cobH; precorrin-8X methylmutase K01833; COG: COG2082 Precorrin isomerase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.931
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
  
 0.930
cobM
KEGG: mta:Moth_1092 1.4e-68 precorrin-4 C11-methyltransferase K03396; COG: COG2875 Precorrin-4 methylase.
 
  
 0.918
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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