Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
kdpE_1Response regulator receiver domain protein; KEGG: eci:UTI89_C0698 2.0e-48 kdpE; transcriptional regulatory protein KdpE K07667; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. (231 aa)    
Predicted Functional Partners:
kdpD_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: cac:CAC3678 1.5e-71 kdpD; sensor protein KdpD (ATPase containing sensor domain and histidine kinase domain) K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
 
 0.995
kdpD_5
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lin:pli0050 9.7e-221 similar to the two components sensor protein kdpD K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99.
 
 0.974
kdpD_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: lmo:lmo2679 1.2e-63 similar to the two components sensor protein kdpD K07646; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99.
 
 
 0.780
ktrA_1
TrkA N-terminal domain protein; COG: COG0569 K+ transport systems, NAD-binding component; Psort location: Cytoplasmic, score: 8.87.
       0.723
kdpD_3
KEGG: lwe:lwe2628 9.5e-50 kdpD; sensor histidine kinase; COG: COG2205 Osmosensitive K+ channel histidine kinase; Psort location: CytoplasmicMembrane, score: 9.97.
 
 
 0.718
cckA
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 0.683
EDS05009.1
Hypothetical protein.
       0.645
ntpJ
KEGG: shn:Shewana3_0031 4.6e-08 potassium uptake protein, TrkH family K00961; COG: COG0168 Trk-type K+ transport systems, membrane components; Psort location: CytoplasmicMembrane, score: 10.00.
       0.645
zraS_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: eco:b2219 1.7e-25 atoS; sensor protein AtoS for response regulator AtoC K07710; COG: COG2202 FOG: PAS/PAC domain; Psort location: CytoplasmicMembrane, score: 9.49.
  
   0.626
WalK_4
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: btl:BALH_4249 3.7e-47 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 0.619
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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