Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HydA_1PAS domain S-box protein; KEGG: cno:NT01CX_0464 1.5e-44 Fe-hydrogenase large subunit family protein K00532; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87. (548 aa)    
Predicted Functional Partners:
hndC_1
4Fe-4S binding domain protein; KEGG: tte:TTE0893 3.3e-243 nuoF; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335; COG: COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Psort location: Cytoplasmic, score: 9.98.
 
 
 
 0.965
EDS05027.1
Stage II sporulation protein E; KEGG: mta:Moth_0103 3.8e-08 serine phosphatase K06382; COG: NOG28446 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.960
hndC_3
4Fe-4S binding domain protein; KEGG: swo:Swol_1701 3.0e-194 NADH dehydrogenase (quinone) K05903; COG: COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.941
EDS05025.1
Hypothetical protein; KEGG: sat:SYN_01647 1.3e-05 NADH-quinone oxidoreductase chain E K00329; COG: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.937
HndB
Hypothetical protein; KEGG: tma:TM0011 1.4e-20 NADP-reducing hydrogenase, subunit B K00329; COG: COG3411 Ferredoxin; Psort location: Cytoplasmic, score: 8.87.
 
 
 
 0.881
HndD_1
Hydrogenase, Fe-only; KEGG: tte:TTE0894 8.9e-195 nuoG; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
 
 
 
0.746
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.727
hypB
Hydrogenase accessory protein HypB; KEGG: tte:TTE2387 0.00013 argK; putative periplasmic protein kinase ArgK and related GTPases of G3E family K07588; COG: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; Psort location: Cytoplasmic, score: 9.98.
  
    0.706
hndA
KEGG: tte:TTE0890 2.1e-42 nuoE; NADH:ubiquinone oxidoreductase 24 kD subunit K00334; COG: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.645
EDS06174.1
4Fe-4S binding domain protein; KEGG: mma:MM1824 0.00011 formylmethanofuran dehydrogenase K00205; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 8.87.
 
 
 
 0.618
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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