Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
EDS05027.1Stage II sporulation protein E; KEGG: mta:Moth_0103 3.8e-08 serine phosphatase K06382; COG: NOG28446 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (396 aa)    
Predicted Functional Partners:
HydA_1
PAS domain S-box protein; KEGG: cno:NT01CX_0464 1.5e-44 Fe-hydrogenase large subunit family protein K00532; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
 
     0.960
EDS05025.1
Hypothetical protein; KEGG: sat:SYN_01647 1.3e-05 NADH-quinone oxidoreductase chain E K00329; COG: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; Psort location: Cytoplasmic, score: 8.87.
 
    0.921
rsbT
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: mav:MAV_0432 1.2e-11 serine/threonine-protein kinase RsbT K08282; COG: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Psort location: Cytoplasmic, score: 8.87.
 
 
 0.916
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.825
HydA_2
4Fe-4S binding domain protein; KEGG: cno:NT01CX_0464 8.1e-24 Fe-hydrogenase large subunit family protein K00532; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
 
     0.792
HndB
Hypothetical protein; KEGG: tma:TM0011 1.4e-20 NADP-reducing hydrogenase, subunit B K00329; COG: COG3411 Ferredoxin; Psort location: Cytoplasmic, score: 8.87.
 
     0.767
EDS05417.1
Hypothetical protein; KEGG: shn:Shewana3_3829 0.0029 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.738
hydG
Iron-only hydrogenase maturation rSAM protein HydG; KEGG: cpr:CPR_2462 2.5e-17 radical SAM domain protein K01012; COG: COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; Psort location: Cytoplasmic, score: 8.87.
  
    0.717
EDS05015.1
Hypothetical protein.
 
     0.712
Cph2
Diguanylate cyclase (GGDEF) domain protein; KEGG: shn:Shewana3_3829 1.9e-35 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) K01745; COG: COG2200 FOG: EAL domain; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.681
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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