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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDExonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (386 aa)    
Predicted Functional Partners:
sbcC
KEGG: ctc:CTC00579 8.6e-110 sbcC; exonuclease sbcC K03546; COG: COG0419 ATPase involved in DNA repair; Psort location: Cytoplasmic, score: 8.87.
 
 0.996
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.974
recF_3
Hypothetical protein; KEGG: fnu:FN0522 0.0021 exonuclease SBCC K03546; COG: COG4717 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score: 7.80.
  
 0.852
recQ
KEGG: cpf:CPF_0327 4.3e-140 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.87.
 
 0.820
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.738
addA
ATP-dependent nuclease subunit A; ATP-dependent DNA helicase.
 
  
 0.714
EDS08604.1
Hypothetical protein.
  
   0.676
addB
ATP-dependent nuclease subunit B; ATP-dependent DNA helicase.
 
  
 0.610
EDS07735.1
DEAD2 domain protein; KEGG: mja:MJ0942 7.3e-20 dinG; ATP-dependent DNA helicase DinG, putative K01529; COG: COG1199 Rad3-related DNA helicases; Psort location: Cytoplasmic, score: 8.87.
  
 0.601
glf
KEGG: msu:MS0661 1.3e-145 glf; UDP-galactopyranose mutase K01854; COG: COG0562 UDP-galactopyranose mutase; Psort location: Cytoplasmic, score: 8.87.
       0.600
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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