| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS05074.1 | dapA | CLOSCI_03683 | CLOSCI_03684 | COG: COG0629 Single-stranded DNA-binding protein; Psort location: Cytoplasmic, score: 8.87. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.591 |
| EDS05074.1 | dapB-2 | CLOSCI_03683 | CLOSCI_03685 | COG: COG0629 Single-stranded DNA-binding protein; Psort location: Cytoplasmic, score: 8.87. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.525 |
| asd | dapA | CLOSCI_01339 | CLOSCI_03684 | KEGG: lsl:LSL_0313 7.3e-145 asd; aspartate-semialdehyde dehydrogenase K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Psort location: Cytoplasmic, score: 8.87. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.938 |
| asd | dapB-2 | CLOSCI_01339 | CLOSCI_03685 | KEGG: lsl:LSL_0313 7.3e-145 asd; aspartate-semialdehyde dehydrogenase K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Psort location: Cytoplasmic, score: 8.87. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.430 |
| asd | hom_1 | CLOSCI_01339 | CLOSCI_03694 | KEGG: lsl:LSL_0313 7.3e-145 asd; aspartate-semialdehyde dehydrogenase K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Psort location: Cytoplasmic, score: 8.87. | KEGG: tte:TTE2620 5.9e-79 thrA2; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87. | 0.955 |
| asd | hom_2 | CLOSCI_01339 | CLOSCI_01150 | KEGG: lsl:LSL_0313 7.3e-145 asd; aspartate-semialdehyde dehydrogenase K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Psort location: Cytoplasmic, score: 8.87. | KEGG: chy:CHY_1912 6.1e-125 hom; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87. | 0.955 |
| asd | lysC_1 | CLOSCI_01339 | CLOSCI_03696 | KEGG: lsl:LSL_0313 7.3e-145 asd; aspartate-semialdehyde dehydrogenase K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Psort location: Cytoplasmic, score: 8.87. | KEGG: chy:CHY_1909 1.7e-120 aspartate kinase, monofunctional class K00928; COG: COG0527 Aspartokinases; Belongs to the aspartokinase family. | 0.971 |
| dapA | EDS05074.1 | CLOSCI_03684 | CLOSCI_03683 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | COG: COG0629 Single-stranded DNA-binding protein; Psort location: Cytoplasmic, score: 8.87. | 0.591 |
| dapA | asd | CLOSCI_03684 | CLOSCI_01339 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | KEGG: lsl:LSL_0313 7.3e-145 asd; aspartate-semialdehyde dehydrogenase K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Psort location: Cytoplasmic, score: 8.87. | 0.938 |
| dapA | dapB | CLOSCI_03684 | CLOSCI_00327 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.981 |
| dapA | dapB-2 | CLOSCI_03684 | CLOSCI_03685 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.991 |
| dapA | dapF-2 | CLOSCI_03684 | CLOSCI_04040 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.552 |
| dapA | gatC | CLOSCI_03684 | CLOSCI_03774 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.561 |
| dapA | hom_1 | CLOSCI_03684 | CLOSCI_03694 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | KEGG: tte:TTE2620 5.9e-79 thrA2; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87. | 0.935 |
| dapA | hom_2 | CLOSCI_03684 | CLOSCI_01150 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | KEGG: chy:CHY_1912 6.1e-125 hom; homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score: 8.87. | 0.924 |
| dapA | lysA | CLOSCI_03684 | CLOSCI_00648 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | KEGG: spn:SP_1978 4.8e-148 diaminopimelate decarboxylase K01586; COG: COG0019 Diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 8.87. | 0.855 |
| dapA | lysC_1 | CLOSCI_03684 | CLOSCI_03696 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | KEGG: chy:CHY_1909 1.7e-120 aspartate kinase, monofunctional class K00928; COG: COG0527 Aspartokinases; Belongs to the aspartokinase family. | 0.609 |
| dapB | dapA | CLOSCI_00327 | CLOSCI_03684 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.981 |
| dapB | dapB-2 | CLOSCI_00327 | CLOSCI_03685 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.920 |
| dapB | dapF-2 | CLOSCI_00327 | CLOSCI_04040 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.507 |