| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AdhE | hisE | CLOSCI_02188 | CLOSCI_00471 | Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | phosphoribosyl-ATP diphosphatase; KEGG: sao:SAOUHSC_03008 3.6e-56 imidazole glycerol phosphate synthase subunit HisF, putative K01663; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the PRA-PH family. | 0.732 |
| AdhE | nadE | CLOSCI_02188 | CLOSCI_01169 | Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.491 |
| AdhE | noxE | CLOSCI_02188 | CLOSCI_03802 | Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.602 |
| AdhE | petC1 | CLOSCI_02188 | CLOSCI_02501 | Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | FAD dependent oxidoreductase; KEGG: mma:MM1656 6.2e-84 oxidoreductase K00100; COG: COG0665 Glycine/D-amino acid oxidases (deaminating); Psort location: Cytoplasmic, score: 8.87. | 0.660 |
| EDS05154.1 | noxE | CLOSCI_03766 | CLOSCI_03802 | Metallo-beta-lactamase domain protein; KEGG: azo:azo0296 1.3e-09 probable metallo-beta-lactamase superfamily protein; COG: COG0491 Zn-dependent hydrolases, including glyoxylases; Psort location: Cytoplasmic, score: 8.87. | NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.637 |
| EDS05191.1 | noxE | CLOSCI_03803 | CLOSCI_03802 | Hypothetical protein. | NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.584 |
| EDS05692.1 | noxE | CLOSCI_03060 | CLOSCI_03802 | Metallo-beta-lactamase family protein; KEGG: hch:HCH_02525 0.00021 Zn-dependent hydrolase, including glyoxylases K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases. | NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.637 |
| EDS05884.1 | noxE | CLOSCI_03011 | CLOSCI_03802 | Hypothetical protein; COG: COG0491 Zn-dependent hydrolases, including glyoxylases. | NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.637 |
| EDS07667.1 | noxE | CLOSCI_01139 | CLOSCI_03802 | Metallo-beta-lactamase domain protein; KEGG: ctc:CTC02196 7.7e-38 hydroxyacylglutathione hydrolase K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases; Psort location: Cytoplasmic, score: 8.87. | NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.637 |
| hisE | AdhE | CLOSCI_00471 | CLOSCI_02188 | phosphoribosyl-ATP diphosphatase; KEGG: sao:SAOUHSC_03008 3.6e-56 imidazole glycerol phosphate synthase subunit HisF, putative K01663; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the PRA-PH family. | Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.732 |
| hisE | nadE | CLOSCI_00471 | CLOSCI_01169 | phosphoribosyl-ATP diphosphatase; KEGG: sao:SAOUHSC_03008 3.6e-56 imidazole glycerol phosphate synthase subunit HisF, putative K01663; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the PRA-PH family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.451 |
| hisE | noxE | CLOSCI_00471 | CLOSCI_03802 | phosphoribosyl-ATP diphosphatase; KEGG: sao:SAOUHSC_03008 3.6e-56 imidazole glycerol phosphate synthase subunit HisF, putative K01663; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the PRA-PH family. | NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.705 |
| hisE | rpmE | CLOSCI_00471 | CLOSCI_01748 | phosphoribosyl-ATP diphosphatase; KEGG: sao:SAOUHSC_03008 3.6e-56 imidazole glycerol phosphate synthase subunit HisF, putative K01663; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the PRA-PH family. | Ribosomal protein L31; Binds the 23S rRNA. | 0.886 |
| nadE | AdhE | CLOSCI_01169 | CLOSCI_02188 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.491 |
| nadE | hisE | CLOSCI_01169 | CLOSCI_00471 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | phosphoribosyl-ATP diphosphatase; KEGG: sao:SAOUHSC_03008 3.6e-56 imidazole glycerol phosphate synthase subunit HisF, putative K01663; COG: COG0139 Phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the PRA-PH family. | 0.451 |
| nadE | noxE | CLOSCI_01169 | CLOSCI_03802 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.594 |
| nadE | petC1 | CLOSCI_01169 | CLOSCI_02501 | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | FAD dependent oxidoreductase; KEGG: mma:MM1656 6.2e-84 oxidoreductase K00100; COG: COG0665 Glycine/D-amino acid oxidases (deaminating); Psort location: Cytoplasmic, score: 8.87. | 0.597 |
| noxE | AdhE | CLOSCI_03802 | CLOSCI_02188 | NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | Aldehyde dehydrogenase (NAD) family protein; KEGG: cpr:CPR_2540 0. aldehyde-alcohol dehydrogenase [includes: alcohol K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.602 |
| noxE | EDS05154.1 | CLOSCI_03802 | CLOSCI_03766 | NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | Metallo-beta-lactamase domain protein; KEGG: azo:azo0296 1.3e-09 probable metallo-beta-lactamase superfamily protein; COG: COG0491 Zn-dependent hydrolases, including glyoxylases; Psort location: Cytoplasmic, score: 8.87. | 0.637 |
| noxE | EDS05191.1 | CLOSCI_03802 | CLOSCI_03803 | NADH oxidase; KEGG: spi:MGAS10750_Spy1021 5.5e-147 nox; NADH oxidase H2O-forming K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | Hypothetical protein. | 0.584 |