| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CysL_3 | fldC_3 | CLOSCI_03978 | CLOSCI_03979 | LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 2.2e-09 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family. | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | 0.612 |
| EDS07315.1 | fldC_3 | CLOSCI_01658 | CLOSCI_03979 | COG: COG5418 Predicted secreted protein; Psort location: Cytoplasmic, score: 8.87. | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | 0.423 |
| HemE_5 | fldC_3 | CLOSCI_01796 | CLOSCI_03979 | KEGG: swo:Swol_0417 7.7e-54 uroporphyrinogen decarboxylase K01599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87. | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | 0.472 |
| HemE_5 | tauA | CLOSCI_01796 | CLOSCI_03980 | KEGG: swo:Swol_0417 7.7e-54 uroporphyrinogen decarboxylase K01599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87. | NMT1/THI5-like protein; COG: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | 0.430 |
| fldC_3 | CysL_3 | CLOSCI_03979 | CLOSCI_03978 | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 2.2e-09 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family. | 0.612 |
| fldC_3 | EDS07315.1 | CLOSCI_03979 | CLOSCI_01658 | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | COG: COG5418 Predicted secreted protein; Psort location: Cytoplasmic, score: 8.87. | 0.423 |
| fldC_3 | HemE_5 | CLOSCI_03979 | CLOSCI_01796 | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | KEGG: swo:Swol_0417 7.7e-54 uroporphyrinogen decarboxylase K01599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87. | 0.472 |
| fldC_3 | hadI | CLOSCI_03979 | CLOSCI_00653 | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 1.6e-18 yjiL; hypothetical protein YjiL K04111; COG: COG3580 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | 0.447 |
| fldC_3 | hgdC | CLOSCI_03979 | CLOSCI_02701 | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 2.1e-42 yjiL; hypothetical protein YjiL K04111; COG: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); Psort location: Cytoplasmic, score: 8.87. | 0.972 |
| fldC_3 | tauA | CLOSCI_03979 | CLOSCI_03980 | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | NMT1/THI5-like protein; COG: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | 0.570 |
| fldC_3 | yedF | CLOSCI_03979 | CLOSCI_02247 | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | Selenium metabolism protein YedF; COG: NOG13230 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87; Belongs to the sulfur carrier protein TusA family. | 0.600 |
| hadI | fldC_3 | CLOSCI_00653 | CLOSCI_03979 | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 1.6e-18 yjiL; hypothetical protein YjiL K04111; COG: COG3580 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | 0.447 |
| hadI | hgdC | CLOSCI_00653 | CLOSCI_02701 | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 1.6e-18 yjiL; hypothetical protein YjiL K04111; COG: COG3580 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 2.1e-42 yjiL; hypothetical protein YjiL K04111; COG: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); Psort location: Cytoplasmic, score: 8.87. | 0.482 |
| hgdC | fldC_3 | CLOSCI_02701 | CLOSCI_03979 | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 2.1e-42 yjiL; hypothetical protein YjiL K04111; COG: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); Psort location: Cytoplasmic, score: 8.87. | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | 0.972 |
| hgdC | hadI | CLOSCI_02701 | CLOSCI_00653 | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 2.1e-42 yjiL; hypothetical protein YjiL K04111; COG: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); Psort location: Cytoplasmic, score: 8.87. | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 1.6e-18 yjiL; hypothetical protein YjiL K04111; COG: COG3580 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. | 0.482 |
| hgdC | yedF | CLOSCI_02701 | CLOSCI_02247 | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 2.1e-42 yjiL; hypothetical protein YjiL K04111; COG: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); Psort location: Cytoplasmic, score: 8.87. | Selenium metabolism protein YedF; COG: NOG13230 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87; Belongs to the sulfur carrier protein TusA family. | 0.505 |
| tauA | HemE_5 | CLOSCI_03980 | CLOSCI_01796 | NMT1/THI5-like protein; COG: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | KEGG: swo:Swol_0417 7.7e-54 uroporphyrinogen decarboxylase K01599; COG: COG0407 Uroporphyrinogen-III decarboxylase; Psort location: Cytoplasmic, score: 8.87. | 0.430 |
| tauA | fldC_3 | CLOSCI_03980 | CLOSCI_03979 | NMT1/THI5-like protein; COG: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components. | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | 0.570 |
| yedF | fldC_3 | CLOSCI_02247 | CLOSCI_03979 | Selenium metabolism protein YedF; COG: NOG13230 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87; Belongs to the sulfur carrier protein TusA family. | 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: eci:UTI89_C5045 1.5e-96 yjiM; hypothetical protein YjiM K04111; COG: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB; Psort location: Cytoplasmic, score: 8.87. | 0.600 |
| yedF | hgdC | CLOSCI_02247 | CLOSCI_02701 | Selenium metabolism protein YedF; COG: NOG13230 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87; Belongs to the sulfur carrier protein TusA family. | Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 2.1e-42 yjiL; hypothetical protein YjiL K04111; COG: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); Psort location: Cytoplasmic, score: 8.87. | 0.505 |