| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CreC | PhoP_5 | CLOSCI_00654 | CLOSCI_00655 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00629 1.2e-71 spaK; subtilin biosynthesis sensor protein SpaK; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.995 |
| CreC | cckA | CLOSCI_00654 | CLOSCI_02760 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00629 1.2e-71 spaK; subtilin biosynthesis sensor protein SpaK; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.490 |
| CreC | cssS_1 | CLOSCI_00654 | CLOSCI_03993 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00629 1.2e-71 spaK; subtilin biosynthesis sensor protein SpaK; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK4751 9.7e-31 resE; sensor histidine kinase; COG: COG5002 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.924 |
| CreC | phoP_4 | CLOSCI_00654 | CLOSCI_03992 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00629 1.2e-71 spaK; subtilin biosynthesis sensor protein SpaK; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.4e-35 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.976 |
| CreC | zraS_1 | CLOSCI_00654 | CLOSCI_02668 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00629 1.2e-71 spaK; subtilin biosynthesis sensor protein SpaK; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: eco:b2219 1.7e-25 atoS; sensor protein AtoS for response regulator AtoC K07710; COG: COG2202 FOG: PAS/PAC domain; Psort location: CytoplasmicMembrane, score: 9.49. | 0.554 |
| MprB | PhoP_5 | CLOSCI_03930 | CLOSCI_00655 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.785 |
| MprB | cckA | CLOSCI_03930 | CLOSCI_02760 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.539 |
| MprB | phoP_4 | CLOSCI_03930 | CLOSCI_03992 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.4e-35 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.811 |
| PhoP_5 | CreC | CLOSCI_00655 | CLOSCI_00654 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00629 1.2e-71 spaK; subtilin biosynthesis sensor protein SpaK; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.995 |
| PhoP_5 | MprB | CLOSCI_00655 | CLOSCI_03930 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 9.7e-47 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.785 |
| PhoP_5 | ResE_9 | CLOSCI_00655 | CLOSCI_00083 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK1343 5.4e-53 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | 0.720 |
| PhoP_5 | WalK_4 | CLOSCI_00655 | CLOSCI_03389 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: btl:BALH_4249 3.7e-47 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.711 |
| PhoP_5 | cckA | CLOSCI_00655 | CLOSCI_02760 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.699 |
| PhoP_5 | cssS_1 | CLOSCI_00655 | CLOSCI_03993 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK4751 9.7e-31 resE; sensor histidine kinase; COG: COG5002 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.972 |
| PhoP_5 | phoP_4 | CLOSCI_00655 | CLOSCI_03992 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.4e-35 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.906 |
| PhoP_5 | phoR_5 | CLOSCI_00655 | CLOSCI_03395 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2750 8.8e-69 histidine kinase, putative; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.726 |
| PhoP_5 | resE_2 | CLOSCI_00655 | CLOSCI_03576 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC01918 8.0e-36 resE; sensor protein ResE; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.701 |
| PhoP_5 | zraS_1 | CLOSCI_00655 | CLOSCI_02668 | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: eco:b2219 1.7e-25 atoS; sensor protein AtoS for response regulator AtoC K07710; COG: COG2202 FOG: PAS/PAC domain; Psort location: CytoplasmicMembrane, score: 9.49. | 0.674 |
| ResE_9 | PhoP_5 | CLOSCI_00083 | CLOSCI_00655 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK1343 5.4e-53 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. | 0.720 |
| ResE_9 | cckA | CLOSCI_00083 | CLOSCI_02760 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK1343 5.4e-53 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. | 0.793 |