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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cssS_1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK4751 9.7e-31 resE; sensor histidine kinase; COG: COG5002 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. (406 aa)    
Predicted Functional Partners:
phoP_4
Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.4e-35 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
  0.995
PhoP_5
Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
  0.972
CreC
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00629 1.2e-71 spaK; subtilin biosynthesis sensor protein SpaK; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
  
  
 
0.924
EDS04858.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.878
EDS04857.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.26.
 
    0.876
yxlF_5
KEGG: noc:Noc_2142 3.3e-37 ABC transporter, ATPase subunit; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
     0.741
walR_10
Response regulator receiver domain protein; KEGG: ava:Ava_3369 1.3e-42 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
   0.661
ResE_9
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK1343 5.4e-53 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36.
 
 
 
 0.641
baeS
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC01918 1.4e-38 resE; sensor protein ResE; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
  
 
   0.631
zraS_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: eco:b2219 1.7e-25 atoS; sensor protein AtoS for response regulator AtoC K07710; COG: COG2202 FOG: PAS/PAC domain; Psort location: CytoplasmicMembrane, score: 9.49.
  
 
   0.626
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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