Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cssS_1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK4751 9.7e-31 resE; sensor histidine kinase; COG: COG5002 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. (406 aa)    
Predicted Functional Partners:
phoP_4
Response regulator receiver domain protein; KEGG: ava:Ava_1878 4.4e-35 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
  0.994
PhoP_5
Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
  0.970
CreC
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00629 1.2e-71 spaK; subtilin biosynthesis sensor protein SpaK; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
  
  
 
0.924
EDS04858.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.876
EDS04857.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.26.
 
    0.871
yxlF_5
KEGG: noc:Noc_2142 3.3e-37 ABC transporter, ATPase subunit; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
     0.740
walR_10
Response regulator receiver domain protein; KEGG: ava:Ava_3369 1.3e-42 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
   0.640
ResE_9
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK1343 5.4e-53 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36.
 
 
 
 0.629
baeS
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC01918 1.4e-38 resE; sensor protein ResE; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
  
 
   0.616
zraS_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: eco:b2219 1.7e-25 atoS; sensor protein AtoS for response regulator AtoC K07710; COG: COG2202 FOG: PAS/PAC domain; Psort location: CytoplasmicMembrane, score: 9.49.
  
 
   0.611
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.