Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
mprF-3Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (331 aa)    
Predicted Functional Partners:
dhaS
Hypothetical protein; COG: COG1309 Transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
 
     0.800
EDS04870.1
FAD dependent oxidoreductase; KEGG: gox:GOX1630 7.5e-12 putative oxidoreductase K00100; COG: COG2509 Uncharacterized FAD-dependent dehydrogenases; Psort location: Cytoplasmic, score: 8.87.
       0.531
mftC_1
Radical SAM domain protein; KEGG: syg:sync_2368 0.0010 arylsulfatase regulator; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87.
       0.488
mprF-2
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
     0.486
hyaD
Glycosyltransferase, group 2 family protein; KEGG: gbe:GbCGDNIH1_2152 7.5e-56 glycosyltransferase K00754; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.430
mntP_2
Hypothetical protein; Probably functions as a manganese efflux pump.
       0.419
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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