| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cca | glmM | CLOSCI_01984 | CLOSCI_04009 | HDIG domain protein; KEGG: ctc:CTC01205 7.4e-104 tRNA nucleotidyltransferase (CCA-adding enzyme) K00974; COG: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Psort location: Cytoplasmic, score: 8.87. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.667 |
| Cca | murC | CLOSCI_01984 | CLOSCI_01977 | HDIG domain protein; KEGG: ctc:CTC01205 7.4e-104 tRNA nucleotidyltransferase (CCA-adding enzyme) K00974; COG: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Psort location: Cytoplasmic, score: 8.87. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.447 |
| WcaJ | glmM | CLOSCI_00159 | CLOSCI_04009 | KEGG: tcx:Tcr_1675 1.8e-70 undecaprenyl-phosphate galactosephosphotransferase K03606; COG: COG2148 Sugar transferases involved in lipopolysaccharide synthesis; Psort location: CytoplasmicMembrane, score: 9.99. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.711 |
| WcaJ | glmS | CLOSCI_00159 | CLOSCI_00153 | KEGG: tcx:Tcr_1675 1.8e-70 undecaprenyl-phosphate galactosephosphotransferase K03606; COG: COG2148 Sugar transferases involved in lipopolysaccharide synthesis; Psort location: CytoplasmicMembrane, score: 9.99. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.685 |
| WcaJ | glmU_1 | CLOSCI_00159 | CLOSCI_01342 | KEGG: tcx:Tcr_1675 1.8e-70 undecaprenyl-phosphate galactosephosphotransferase K03606; COG: COG2148 Sugar transferases involved in lipopolysaccharide synthesis; Psort location: CytoplasmicMembrane, score: 9.99. | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 2.4e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | 0.536 |
| cdaA | glmM | CLOSCI_02389 | CLOSCI_04009 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.872 |
| glmM | Cca | CLOSCI_04009 | CLOSCI_01984 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | HDIG domain protein; KEGG: ctc:CTC01205 7.4e-104 tRNA nucleotidyltransferase (CCA-adding enzyme) K00974; COG: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Psort location: Cytoplasmic, score: 8.87. | 0.667 |
| glmM | WcaJ | CLOSCI_04009 | CLOSCI_00159 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | KEGG: tcx:Tcr_1675 1.8e-70 undecaprenyl-phosphate galactosephosphotransferase K03606; COG: COG2148 Sugar transferases involved in lipopolysaccharide synthesis; Psort location: CytoplasmicMembrane, score: 9.99. | 0.711 |
| glmM | cdaA | CLOSCI_04009 | CLOSCI_02389 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.872 |
| glmM | glmS | CLOSCI_04009 | CLOSCI_00153 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.971 |
| glmM | glmU_1 | CLOSCI_04009 | CLOSCI_01342 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 2.4e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | 0.597 |
| glmM | murA | CLOSCI_04009 | CLOSCI_00968 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.657 |
| glmM | murB | CLOSCI_04009 | CLOSCI_02540 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.649 |
| glmM | murC | CLOSCI_04009 | CLOSCI_01977 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.661 |
| glmM | nagA | CLOSCI_04009 | CLOSCI_01435 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | KEGG: tte:TTE0232 6.9e-69 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase; Psort location: Cytoplasmic, score: 8.87. | 0.926 |
| glmM | nagB | CLOSCI_04009 | CLOSCI_03190 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.930 |
| glmS | WcaJ | CLOSCI_00153 | CLOSCI_00159 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | KEGG: tcx:Tcr_1675 1.8e-70 undecaprenyl-phosphate galactosephosphotransferase K03606; COG: COG2148 Sugar transferases involved in lipopolysaccharide synthesis; Psort location: CytoplasmicMembrane, score: 9.99. | 0.685 |
| glmS | glmM | CLOSCI_00153 | CLOSCI_04009 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.971 |
| glmS | glmU_1 | CLOSCI_00153 | CLOSCI_01342 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Bacterial transferase hexapeptide repeat protein; KEGG: pcu:pc1997 2.4e-34 glmU; putative UDP-N-acetylglucosamine diphosphorylase K00972; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 8.87. | 0.784 |
| glmS | murA | CLOSCI_00153 | CLOSCI_00968 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.439 |