STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS04888.1Hypothetical protein. (74 aa)    
Predicted Functional Partners:
EDS04887.1
Hypothetical protein; COG: NOG18028 non supervised orthologous group.
  
    0.807
ydbD_1
Hypothetical protein; KEGG: bpm:BURPS1710b_A1348 3.1e-25 DNA mismatch endonuclease K07217; COG: COG3546 Mn-containing catalase; Psort location: Cytoplasmic, score: 8.87.
  
    0.784
EDS08609.1
Glycosyltransferase, group 2 family protein; KEGG: stm:STM2085 7.7e-54 rfbN; LPS side chain defect: rhamnosyl transferase K00754; COG: COG0463 Glycosyltransferases involved in cell wall biogenesis; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.654
resE_6
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK1343 2.0e-62 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase.
  
    0.553
srrA_3
Response regulator receiver domain protein; KEGG: ava:Ava_1878 6.3e-43 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
       0.534
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.454
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.435
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.422
lpdA-2
Dihydrolipoyl dehydrogenase; KEGG: tde:TDE1629 2.0e-78 lpdA; dihydrolipoamide dehydrogenase K00382; COG: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Psort location: Cytoplasmic, score: 9.98.
   
   0.411
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
     
 0.410
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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