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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapF-2Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (285 aa)    
Predicted Functional Partners:
dapL
LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.
 
 0.943
lysA
KEGG: spn:SP_1978 4.8e-148 diaminopimelate decarboxylase K01586; COG: COG0019 Diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 8.87.
  
 0.937
Ddh
Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate.
     
 0.914
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
  
  
 
0.914
asd
KEGG: lsl:LSL_0313 7.3e-145 asd; aspartate-semialdehyde dehydrogenase K00133; COG: COG0136 Aspartate-semialdehyde dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.698
addA
ATP-dependent nuclease subunit A; ATP-dependent DNA helicase.
     
 0.688
btrK
Pyridoxal-dependent decarboxylase, C-terminal sheet domain protein; KEGG: nmu:Nmul_A2669 5.4e-30 Orn/DAP/Arg decarboxylase 2 K01586; COG: COG0019 Diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 8.87.
  
 0.686
addB
ATP-dependent nuclease subunit B; ATP-dependent DNA helicase.
       0.686
EDS04904.1
Hypothetical protein; KEGG: ctc:CTC01157 1.6e-13 phosphoesterase; COG: COG3326 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.26.
       0.682
rhaS_2
Transcriptional regulator, AraC family; KEGG: bcz:BCZK2914 2.5e-10 adaA; methylphosphotriester-DNA alkyltransferase K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 9.98; ORF located using Blastx.
 
     0.645
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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