STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addBATP-dependent nuclease subunit B; ATP-dependent DNA helicase. (1141 aa)    
Predicted Functional Partners:
addA
ATP-dependent nuclease subunit A; ATP-dependent DNA helicase.
 
 
 0.999
rep
Hypothetical protein; KEGG: gbe:GbCGDNIH1_1179 1.3e-76 DNA helicase II K01529; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.902
EDS04904.1
Hypothetical protein; KEGG: ctc:CTC01157 1.6e-13 phosphoesterase; COG: COG3326 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.26.
       0.788
dapF-2
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
       0.685
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.659
trmK
Hypothetical protein; KEGG: fnu:FN0907 0.0071 ribosomal RNA small subunit methyltransferase C K00564; COG: COG2384 Predicted SAM-dependent methyltransferase; Psort location: Cytoplasmic, score: 8.87.
 
     0.575
sbcC
KEGG: ctc:CTC00579 8.6e-110 sbcC; exonuclease sbcC K03546; COG: COG0419 ATPase involved in DNA repair; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.536
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
   
 0.488
rhaS_2
Transcriptional regulator, AraC family; KEGG: bcz:BCZK2914 2.5e-10 adaA; methylphosphotriester-DNA alkyltransferase K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 9.98; ORF located using Blastx.
       0.463
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
   
 0.456
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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