STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS04904.1Hypothetical protein; KEGG: ctc:CTC01157 1.6e-13 phosphoesterase; COG: COG3326 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.26. (88 aa)    
Predicted Functional Partners:
addA
ATP-dependent nuclease subunit A; ATP-dependent DNA helicase.
 
     0.812
addB
ATP-dependent nuclease subunit B; ATP-dependent DNA helicase.
       0.784
dapF-2
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
       0.682
rhaS_2
Transcriptional regulator, AraC family; KEGG: bcz:BCZK2914 2.5e-10 adaA; methylphosphotriester-DNA alkyltransferase K00567; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 9.98; ORF located using Blastx.
       0.463
topB_2
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
 
     0.415
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.