| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS08290.1 | carA | CLOSCI_00601 | CLOSCI_02024 | ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 2.1e-108 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | KEGG: ldb:Ldb1070 3.0e-107 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | 0.776 |
| EDS08290.1 | gltA | CLOSCI_00601 | CLOSCI_00600 | ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 2.1e-108 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | KEGG: cno:NT01CX_0466 2.6e-179 gltA; glutamate synthase (NADPH), homotetrameric K00264; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | 0.997 |
| EDS08290.1 | pyrB | CLOSCI_00601 | CLOSCI_00682 | ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 2.1e-108 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | KEGG: cac:CAC2654 6.3e-107 aspartate carbamoyltransferase catalytic subunit K00609; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.807 |
| EDS08290.1 | pyrC | CLOSCI_00601 | CLOSCI_04057 | ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 2.1e-108 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.672 |
| EDS08290.1 | pyrD | CLOSCI_00601 | CLOSCI_04060 | ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 2.1e-108 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. | 0.974 |
| EDS08290.1 | pyrE | CLOSCI_00601 | CLOSCI_04061 | ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 2.1e-108 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.657 |
| EDS08290.1 | pyrF | CLOSCI_00601 | CLOSCI_04058 | ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 2.1e-108 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | KEGG: blo:BL0791 7.1e-67 pyrF; orotidine 5'-phosphate decarboxylase K01591; COG: COG0284 Orotidine-5-phosphate decarboxylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.814 |
| EDS08290.1 | sfrB_1 | CLOSCI_00601 | CLOSCI_02190 | ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 2.1e-108 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | Pyridine nucleotide-disulfide oxidoreductase; KEGG: cte:CT0282 6.4e-82 glutamate synthase (NADPH) small chain K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | 0.905 |
| EDS08290.1 | uraA | CLOSCI_00601 | CLOSCI_02483 | ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 2.1e-108 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | Putative permease; KEGG: fal:FRAAL4724 0.00071 putative sulphate transporter and carbonic anhidrase K01672; COG: COG2233 Xanthine/uracil permeases; Psort location: CytoplasmicMembrane, score: 10.00. | 0.607 |
| carA | EDS08290.1 | CLOSCI_02024 | CLOSCI_00601 | KEGG: ldb:Ldb1070 3.0e-107 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 2.1e-108 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | 0.776 |
| carA | gltA | CLOSCI_02024 | CLOSCI_00600 | KEGG: ldb:Ldb1070 3.0e-107 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | KEGG: cno:NT01CX_0466 2.6e-179 gltA; glutamate synthase (NADPH), homotetrameric K00264; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | 0.902 |
| carA | pyrB | CLOSCI_02024 | CLOSCI_00682 | KEGG: ldb:Ldb1070 3.0e-107 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | KEGG: cac:CAC2654 6.3e-107 aspartate carbamoyltransferase catalytic subunit K00609; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.999 |
| carA | pyrC | CLOSCI_02024 | CLOSCI_04057 | KEGG: ldb:Ldb1070 3.0e-107 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.996 |
| carA | pyrD | CLOSCI_02024 | CLOSCI_04060 | KEGG: ldb:Ldb1070 3.0e-107 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. | 0.952 |
| carA | pyrE | CLOSCI_02024 | CLOSCI_04061 | KEGG: ldb:Ldb1070 3.0e-107 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.935 |
| carA | pyrF | CLOSCI_02024 | CLOSCI_04058 | KEGG: ldb:Ldb1070 3.0e-107 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | KEGG: blo:BL0791 7.1e-67 pyrF; orotidine 5'-phosphate decarboxylase K01591; COG: COG0284 Orotidine-5-phosphate decarboxylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.920 |
| carA | pyrK | CLOSCI_02024 | CLOSCI_04059 | KEGG: ldb:Ldb1070 3.0e-107 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | Oxidoreductase NAD-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.938 |
| carA | uraA | CLOSCI_02024 | CLOSCI_02483 | KEGG: ldb:Ldb1070 3.0e-107 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | Putative permease; KEGG: fal:FRAAL4724 0.00071 putative sulphate transporter and carbonic anhidrase K01672; COG: COG2233 Xanthine/uracil permeases; Psort location: CytoplasmicMembrane, score: 10.00. | 0.844 |
| gltA | EDS08290.1 | CLOSCI_00600 | CLOSCI_00601 | KEGG: cno:NT01CX_0466 2.6e-179 gltA; glutamate synthase (NADPH), homotetrameric K00264; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | ferredoxin--NADP+ reductase, subunit alpha; KEGG: cno:NT01CX_0467 2.1e-108 glutamate synthase, small subunit K00226; COG: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | 0.997 |
| gltA | carA | CLOSCI_00600 | CLOSCI_02024 | KEGG: cno:NT01CX_0466 2.6e-179 gltA; glutamate synthase (NADPH), homotetrameric K00264; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98. | KEGG: ldb:Ldb1070 3.0e-107 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. | 0.902 |