| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS04923.1 | EDS04924.1 | CLOSCI_04062 | CLOSCI_04063 | Hypothetical protein. | VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.26. | 0.735 |
| EDS04923.1 | EDS04925.1 | CLOSCI_04062 | CLOSCI_04064 | Hypothetical protein. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.692 |
| EDS04923.1 | EDS04926.1 | CLOSCI_04062 | CLOSCI_04065 | Hypothetical protein. | Hypothetical protein; KEGG: hwa:HQ1074A 4.2e-07 pepB; aminopeptidase (similar to leucyl aminopeptidase, aminopeptidase T) K01255; COG: COG2309 Leucyl aminopeptidase (aminopeptidase T); Psort location: Cytoplasmic, score: 8.87. | 0.745 |
| EDS04923.1 | purE | CLOSCI_04062 | CLOSCI_04066 | Hypothetical protein. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.528 |
| EDS04923.1 | purM | CLOSCI_04062 | CLOSCI_04067 | Hypothetical protein. | Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: gka:GK0265 2.9e-102 phosphoribosylaminoimidazole synthetase K01933; COG: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; Psort location: Cytoplasmic, score: 8.87. | 0.441 |
| EDS04923.1 | purN | CLOSCI_04062 | CLOSCI_04068 | Hypothetical protein. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.441 |
| EDS04923.1 | pyrD | CLOSCI_04062 | CLOSCI_04060 | Hypothetical protein. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. | 0.589 |
| EDS04923.1 | pyrE | CLOSCI_04062 | CLOSCI_04061 | Hypothetical protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.772 |
| EDS04923.1 | pyrF | CLOSCI_04062 | CLOSCI_04058 | Hypothetical protein. | KEGG: blo:BL0791 7.1e-67 pyrF; orotidine 5'-phosphate decarboxylase K01591; COG: COG0284 Orotidine-5-phosphate decarboxylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.502 |
| EDS04923.1 | pyrK | CLOSCI_04062 | CLOSCI_04059 | Hypothetical protein. | Oxidoreductase NAD-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.576 |
| EDS04924.1 | EDS04923.1 | CLOSCI_04063 | CLOSCI_04062 | VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.26. | Hypothetical protein. | 0.735 |
| EDS04924.1 | EDS04925.1 | CLOSCI_04063 | CLOSCI_04064 | VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.26. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.805 |
| EDS04924.1 | EDS04926.1 | CLOSCI_04063 | CLOSCI_04065 | VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.26. | Hypothetical protein; KEGG: hwa:HQ1074A 4.2e-07 pepB; aminopeptidase (similar to leucyl aminopeptidase, aminopeptidase T) K01255; COG: COG2309 Leucyl aminopeptidase (aminopeptidase T); Psort location: Cytoplasmic, score: 8.87. | 0.873 |
| EDS04924.1 | purE | CLOSCI_04063 | CLOSCI_04066 | VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.26. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.700 |
| EDS04924.1 | purM | CLOSCI_04063 | CLOSCI_04067 | VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.26. | Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: gka:GK0265 2.9e-102 phosphoribosylaminoimidazole synthetase K01933; COG: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; Psort location: Cytoplasmic, score: 8.87. | 0.555 |
| EDS04924.1 | purN | CLOSCI_04063 | CLOSCI_04068 | VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.26. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.556 |
| EDS04924.1 | pyrD | CLOSCI_04063 | CLOSCI_04060 | VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.26. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. | 0.640 |
| EDS04924.1 | pyrE | CLOSCI_04063 | CLOSCI_04061 | VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.26. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.759 |
| EDS04924.1 | pyrF | CLOSCI_04063 | CLOSCI_04058 | VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.26. | KEGG: blo:BL0791 7.1e-67 pyrF; orotidine 5'-phosphate decarboxylase K01591; COG: COG0284 Orotidine-5-phosphate decarboxylase; Psort location: Cytoplasmic, score: 8.87; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.570 |
| EDS04924.1 | pyrK | CLOSCI_04063 | CLOSCI_04059 | VanZ-like protein; COG: COG4767 Glycopeptide antibiotics resistance protein; Psort location: CytoplasmicMembrane, score: 9.26. | Oxidoreductase NAD-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). | 0.561 |