STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (452 aa)    
Predicted Functional Partners:
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
  
 0.834
recX
Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
 
  
 0.762
clpC
ATPase family associated with various cellular activities (AAA); KEGG: sab:SAB0475 4.3e-227 clpC; endopeptidase K03696; COG: COG0542 ATPases with chaperone activity, ATP-binding subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the ClpA/ClpB family.
  
  
 0.717
EDS04936.1
Hypothetical protein.
       0.689
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
   
 0.662
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
   
 0.653
EDS04938.1
Hypothetical protein; Psort location: Extracellular, score: 8.82.
       0.623
EDS04939.1
Hypothetical protein; Psort location: Extracellular, score: 8.82.
       0.595
YtrA_1
KEGG: btk:BT9727_3817 6.4e-11 transcriptional regulator, GntR family K07979; COG: COG1725 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
       0.558
pcrA
KEGG: bha:BH0648 2.5e-190 pcrA; ATP-dependent DNA helicase K03657; COG: COG0210 Superfamily I DNA and RNA helicases; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.542
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.