STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiWProtein ThiW; KEGG: sdy:SDY_2579 0.0058 putative sensor protein K07704; Psort location: CytoplasmicMembrane, score: 9.46. (172 aa)    
Predicted Functional Partners:
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
 
     0.867
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
     0.837
EFB77358.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.773
thiD
KEGG: blo:BL0113 2.6e-76 thiD; phosphomethylpyrimidine kinase K00877:K00941.
 
   
 0.690
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
       0.592
EFB77359.1
Transcriptional regulator, AraC family; KEGG: eca:ECA2408 3.4e-19 paeX; pectin acetylesterase; Psort location: Cytoplasmic, score: 9.26.
       0.451
EFB75603.1
Cobalt transport protein; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.401
Your Current Organism:
Subdoligranulum variabile
NCBI taxonomy Id: 411471
Other names: S. variabile DSM 15176, Subdoligranulum variabile DSM 15176
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