STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)    
Predicted Functional Partners:
udk
Uridine kinase; KEGG: bca:BCE_4462 8.7e-62 udk; uridine kinase K00876; Psort location: Cytoplasmic, score: 8.96.
 
 0.996
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.971
EFB76787.1
Phosphoribulokinase/uridine kinase family protein; KEGG: tma:TM0751 5.4e-37 uridine kinase K00876; Psort location: Cytoplasmic, score: 8.96.
  
 0.963
EFB75105.1
Hypothetical protein; KEGG: dra:DR0159 6.4e-07 uridine kinase K00876; Psort location: Cytoplasmic, score: 8.96.
  
 0.963
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.944
rpiB
KEGG: tte:TTE0146 9.3e-42 rpiB; ribose 5-phosphate isomerase B K01808; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.930
pyrF
KEGG: ctc:CTC02381 5.7e-81 pyrF; orotidine 5'-phosphate decarboxylase K01591; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.923
rpiB-2
Ribose-5-phosphate isomerase B; KEGG: cno:NT01CX_0543 5.7e-42 rpiB; ribose 5-phosphate isomerase B K01806; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.922
pyn
KEGG: gka:GK2312 2.8e-120 pyrimidine-nucleoside phosphorylase (PYNP) K00756.
  
 
 0.907
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.853
Your Current Organism:
Subdoligranulum variabile
NCBI taxonomy Id: 411471
Other names: S. variabile DSM 15176, Subdoligranulum variabile DSM 15176
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