STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFB77156.1Sigma-70 region 2; KEGG: reh:H16_A2725 2.8e-16 rpoD1; DNA-directed RNA polymerase sigma subunit (RpoD) K00960; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family. (232 aa)    
Predicted Functional Partners:
EFB77154.1
Putative anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
  
 0.980
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.974
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.928
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.898
EFB75410.1
Sigma-70 region 2; KEGG: reh:H16_A2373 7.2e-09 rpoS; DNA-directed RNA polymerase sigma subunit (sigma38) K00960; Belongs to the sigma-70 factor family.
  
   
 0.783
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.777
EFB76798.1
Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.776
EFB74909.1
KEGG: bha:BH0078 1.6e-31 spoIIE; stage II sporulation protein E K06382; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.727
spoIVB
SpoIVB peptidase; KEGG: btl:BALH_3781 4.9e-52 spoIVB; stage IV sporulation protein B.
  
  
 0.702
spoVAD
Stage V sporulation protein AD.
 
    0.702
Your Current Organism:
Subdoligranulum variabile
NCBI taxonomy Id: 411471
Other names: S. variabile DSM 15176, Subdoligranulum variabile DSM 15176
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