STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pynKEGG: gka:GK2312 2.8e-120 pyrimidine-nucleoside phosphorylase (PYNP) K00756. (438 aa)    
Predicted Functional Partners:
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
 0.997
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
 
 0.991
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.907
deoD
KEGG: ftl:FTL_1461 3.5e-58 purine nucleoside phosphorylase K03784.
 
 
 0.894
EFB76822.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
  
 0.891
EFB74757.1
Hypothetical protein; KEGG: bur:Bcep18194_A4171 2.5e-06 alpha/beta hydrolase K01054.
  
 
 0.884
tdk
Thymidine kinase; KEGG: cpe:CPE2204 2.1e-60 tdk; thymidine kinase K00857; Psort location: Cytoplasmic, score: 8.96.
    
 0.867
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
 
 
 0.863
udk
Uridine kinase; KEGG: bca:BCE_4462 8.7e-62 udk; uridine kinase K00876; Psort location: Cytoplasmic, score: 8.96.
    
 0.833
EFB75105.1
Hypothetical protein; KEGG: dra:DR0159 6.4e-07 uridine kinase K00876; Psort location: Cytoplasmic, score: 8.96.
    
 0.832
Your Current Organism:
Subdoligranulum variabile
NCBI taxonomy Id: 411471
Other names: S. variabile DSM 15176, Subdoligranulum variabile DSM 15176
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