STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purMPhosphoribosylformylglycinamidine cyclo-ligase; KEGG: bha:BH0631 8.1e-98 purM; phosphoribosylaminoimidazole synthetase K01933. (347 aa)    
Predicted Functional Partners:
purF
Amidophosphoribosyltransferase; KEGG: cac:CAC1392 1.7e-97 purF; glutamine phosphoribosylpyrophosphate amidotransferase K00764; Psort location: Cytoplasmic, score: 8.96.
 
 0.999
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 0.999
purD
KEGG: mta:Moth_2043 2.8e-111 phosphoribosylamine--glycine ligase K01945; Psort location: Cytoplasmic, score: 8.96; Belongs to the GARS family.
 
 0.999
EFB75825.1
KEGG: blo:BL1108 0. purL; phosphoribosylformylglycinamidine synthase K01952.
 
 
 0.999
EFB75823.1
AICARFT/IMPCHase bienzyme; KEGG: xla:443576 1.2e-117 LOC443576; hypothetical protein LOC443576 K00602:K01492.
 
  
 0.993
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
 
 0.990
purC
KEGG: cpf:CPF_0673 4.9e-68 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Belongs to the SAICAR synthetase family.
 
 
 0.986
purB
Adenylosuccinate lyase; KEGG: cpf:CPF_1922 4.3e-163 purB; adenylosuccinate lyase K01756; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.966
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
    
 0.911
EFB75822.1
KEGG: mka:MK0087 1.8e-08 IMP cyclohydrolase K01492.
     
 0.835
Your Current Organism:
Subdoligranulum variabile
NCBI taxonomy Id: 411471
Other names: S. variabile DSM 15176, Subdoligranulum variabile DSM 15176
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