STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDExonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (376 aa)    
Predicted Functional Partners:
EFB75097.1
Hypothetical protein; KEGG: ctc:CTC00579 1.2e-40 sbcC; exonuclease sbcC K03546; Psort location: Cytoplasmic, score: 8.96.
 0.999
EFB75091.1
KEGG: azo:azo0200 1.2e-47 sbcC; exonuclease SbcC, putative K01146; Psort location: Cytoplasmic, score: 8.96.
 
 0.999
polA
KEGG: sth:STH848 2.5e-183 DNA polymerase I K02335.
  
 0.998
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.976
EFB76251.1
Metallo-beta-lactamase domain protein; KEGG: shn:Shewana3_0537 6.2e-84 aspartate kinase K00928.
  
 0.922
asnS
asparagine--tRNA ligase; KEGG: cno:NT01CX_1233 2.7e-161 asnS; asparaginyl-tRNA synthetase K01893; Psort location: Cytoplasmic, score: 9.26.
  
  0.878
EFB76834.1
Hypothetical protein; KEGG: aeh:Mlg_1156 2.7e-28 helicase C2 K03722; Psort location: Cytoplasmic, score: 8.96.
   
 0.865
EFB76835.1
Hypothetical protein; KEGG: vch:VC1990 7.3e-18 ATP-dependent helicase, DinG family K03722.
   
 0.865
EFB76711.1
DEAD2 domain protein; KEGG: cjk:jk0491 4.6e-14 dinG; Rad3-related DNA helicases K03722.
  
 0.865
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.845
Your Current Organism:
Subdoligranulum variabile
NCBI taxonomy Id: 411471
Other names: S. variabile DSM 15176, Subdoligranulum variabile DSM 15176
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.