Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (534 aa)    
Predicted Functional Partners:
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.955
rpsB
Ribosomal protein S2; KEGG: apb:SAR116_0519 1.1e-60 30S ribosomal protein S2 K02967; Psort location: Cytoplasmic, score: 9.97; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.878
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.865
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.855
ERJ96499.1
Putative protein MazG; KEGG: ain:Acin_0784 1.0e-48 mazG; nucleoside-triphosphate pyrophosphatase K02499; Psort location: Cytoplasmic, score: 7.50.
 
  
  0.851
ERJ96901.1
KEGG: eel:EUBELI_01571 0. anaerobic ribonucleoside triphosphate reductase; K00527 ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 7.50.
     
 0.832
ERJ96787.1
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
   
  0.808
ERJ93261.1
Hydrolase, NUDIX family; KEGG: str:Sterm_2202 8.5e-24 polynucleotide adenylyltransferase/metal dependent phosphohydrolase; K00974 tRNA nucleotidyltransferase (CCA-adding enzyme); Psort location: Cytoplasmic, score: 7.50.
    
  0.793
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.784
ERJ94620.1
Hypothetical protein.
       0.773
Your Current Organism:
Ruminococcus callidus
NCBI taxonomy Id: 411473
Other names: R. callidus ATCC 27760, Ruminococcus callidus ATCC 27760
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